Detalhe da pesquisa
1.
A Review of Approaches to Potentiate the Activity of Temozolomide against Glioblastoma to Overcome Resistance.
Int J Mol Sci
; 25(6)2024 Mar 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-38542190
2.
Bone marrow regeneration requires mitochondrial transfer from donor Cx43-expressing hematopoietic progenitors to stroma.
Blood
; 136(23): 2607-2619, 2020 12 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-32929449
3.
Brain pharmacokinetics and metabolism of the AMP-activated protein kinase selective inhibitor SBI-0206965, an investigational agent for the treatment of glioblastoma.
Invest New Drugs
; 40(5): 944-952, 2022 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-35802287
4.
Copb2 is essential for embryogenesis and hypomorphic mutations cause human microcephaly.
Hum Mol Genet
; 26(24): 4836-4848, 2017 12 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29036432
5.
Discrete mechanisms of mTOR and cell cycle regulation by AMPK agonists independent of AMPK.
Proc Natl Acad Sci U S A
; 111(4): E435-44, 2014 Jan 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-24474794
6.
The protein tyrosine phosphatase Shp2 is required for the generation of oligodendrocyte progenitor cells and myelination in the mouse telencephalon.
J Neurosci
; 34(10): 3767-78, 2014 Mar 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-24599474
7.
A Phase 0/I Pharmacokinetic and Pharmacodynamics and Safety and Tolerability Study of Letrozole in Combination with Standard Therapy in Recurrent High-Grade Gliomas.
Clin Cancer Res
; 30(10): 2068-2077, 2024 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-38530160
8.
Chronic AMPK inactivation slows SHH medulloblastoma progression by inhibiting mTORC1 signaling and depleting tumor stem cells.
iScience
; 26(12): 108443, 2023 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-38094249
9.
Nampt/PBEF/Visfatin regulates insulin secretion in beta cells as a systemic NAD biosynthetic enzyme.
Cell Metab
; 6(5): 363-75, 2007 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-17983582
10.
AMPK in the brain: its roles in glucose and neural metabolism.
FEBS J
; 289(8): 2247-2262, 2022 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-34355526
11.
Potentiation of temozolomide activity against glioblastoma cells by aromatase inhibitor letrozole.
Cancer Chemother Pharmacol
; 90(4): 345-356, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-36050497
12.
Analysis of reactive astrogliosis in mouse brain using in situ hybridization combined with immunohistochemistry.
STAR Protoc
; 2(1): 100375, 2021 03 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-33718893
13.
Mechanisms of stearoyl CoA desaturase inhibitor sensitivity and acquired resistance in cancer.
Sci Adv
; 7(7)2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33568479
14.
Insight on Transcriptional Regulation of the Energy Sensing AMPK and Biosynthetic mTOR Pathway Genes.
Front Cell Dev Biol
; 8: 671, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32903688
15.
AMPK-Regulated Astrocytic Lactate Shuttle Plays a Non-Cell-Autonomous Role in Neuronal Survival.
Cell Rep
; 32(9): 108092, 2020 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32877674
16.
Spatiotemporal differences in CXCL12 expression and cyclic AMP underlie the unique pattern of optic glioma growth in neurofibromatosis type 1.
Cancer Res
; 67(18): 8588-95, 2007 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-17875698
17.
Plasma and brain pharmacokinetics of letrozole and drug interaction studies with temozolomide in NOD-scid gamma mice and sprague dawley rats.
Cancer Chemother Pharmacol
; 83(1): 81-89, 2019 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30357450
18.
Neurofibromatosis 1: closing the GAP between mice and men.
Curr Opin Genet Dev
; 13(1): 20-7, 2003 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-12573431
19.
Compound C/Dorsomorphin: Its Use and Misuse as an AMPK Inhibitor.
Methods Mol Biol
; 1732: 195-202, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-29480476
20.
Publisher Correction: AMP kinase promotes glioblastoma bioenergetics and tumour growth.
Nat Cell Biol
; 20(10): 1228, 2018 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-30089841